BDBM50116414 2-(2,6-Dichloro-phenylamino)-6-isobutyl-6-methyl-1,6-dihydro-imidazo[4,5-h]isoquinoline-7,9-dione::CHEMBL427301

SMILES CC(C)CC1(C)C(=O)NC(=O)c2c1ccc1nc(Nc3c(Cl)cccc3Cl)[nH]c21

InChI Key InChIKey=STSXYWPNJGCBFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116414   

TargetTyrosine-protein kinase Lck(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116414(2-(2,6-Dichloro-phenylamino)-6-isobutyl-6-methyl-1...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against recombinant human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed