BDBM50116410 2-(2,6-Dimethyl-phenylamino)-6,6-dimethyl-1,6-dihydro-imidazo[4,5-h]isoquinoline-7,9-dione::CHEMBL114963

SMILES Cc1cccc(C)c1Nc1nc2ccc3c(C(=O)NC(=O)C3(C)C)c2[nH]1

InChI Key InChIKey=IPSXGXZJTMZRIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116410   

TargetTyrosine-protein kinase Lck(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116410(2-(2,6-Dimethyl-phenylamino)-6,6-dimethyl-1,6-dihy...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against recombinant human p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed