BDBM50116387 2-Chloro-4-[5-(2-chloro-4-hydroxy-phenyl)-4,5-dihydro-1H-imidazol-4-yl]-phenol::3-chloro-4-[(4S,5R)-4-(2-chloro-4-hydroxyphenyl)-4,5-dihydro-1H-imidazol-5-yl]phenol::3-chloro-4-[4-(2-chloro-4-hydroxyphenyl)-(4S,5R)-4,5-dihydro-1H-5-imidazolyl]phenol::4,4'-((4S,5R)-4,5-dihydro-1H-imidazole-4,5-diyl)bis(3-chlorophenol)::CHEMBL114159

SMILES Oc1ccc([C@H]2NC=N[C@H]2c2ccc(O)cc2Cl)c(Cl)c1

InChI Key InChIKey=AKCOSDIBWNSUIS-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116387   

TargetEstrogen receptor(Human)
Freie Universitat Berlin

Curated by ChEMBL
LigandPNGBDBM50116387(3-chloro-4-[(4S,5R)-4-(2-chloro-4-hydroxyphenyl)-4...)
Affinity DataEC50:  380nMAssay Description:Transactivation of ERalpha in human MCF7-2a cells assessed as luciferase reporter gene expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Freie Universitat Berlin

Curated by ChEMBL
LigandPNGBDBM50116387(3-chloro-4-[(4S,5R)-4-(2-chloro-4-hydroxyphenyl)-4...)
Affinity DataEC50:  380nMAssay Description:Concentration required to activate luciferase expression in MCF-7-2a cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Freie Universitat Berlin

Curated by ChEMBL
LigandPNGBDBM50116387(3-chloro-4-[(4S,5R)-4-(2-chloro-4-hydroxyphenyl)-4...)
Affinity DataEC50:  380nMAssay Description:Agonist activity in transcriptional activation assay in MCF-7-2a cells compared to estradiol E2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed