BDBM50116253 2-{[3-Carboxy-3-(4-methylamino-benzoylamino)-propyl]-hydroxy-phosphinoyloxy}-pentanedioic acid::CHEMBL304352

SMILES CNc1ccc(cc1)C(=O)N[C@@H](CCP(O)(=O)O[C@@H](CCC(O)=O)C(O)=O)C(O)=O

InChI Key InChIKey=UZGMPYWXEGRHGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116253   

TargetFolylpolyglutamate synthase, mitochondrial(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116253(2-{[3-Carboxy-3-(4-methylamino-benzoylamino)-propy...)
Affinity DataIC50: 5.70E+3nMAssay Description:Compound was evaluated for its ability to inhibit Folyl-poly-gamma-glutamyl synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50116253(2-{[3-Carboxy-3-(4-methylamino-benzoylamino)-propy...)
Affinity DataIC50: 4nMAssay Description:Compound was evaluated for its ability to inhibit Glutamate carboxypeptidase-II using N-acetyl-L-aspartyl-[3H]L-glutamate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed