BDBM50116207 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-thiophen-2-ylmethyl}-azepan-2-one::CHEMBL69339

SMILES COc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)s2)CC1

InChI Key InChIKey=LYKQJJQHRZAFLA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116207   

TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed