BDBM50116039 3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl-[1,2,3]triazol-2-yl]-pyridine-2,6-diamine::CHEMBL291427

SMILES Nc1nc(N)c(F)c(c1F)-n1nc(c(n1)-c1ccc(F)cc1)-c1ccncc1

InChI Key InChIKey=FIWNDQKXIBUIND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116039   

TargetProstaglandin G/H synthase 1(Sheep)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116039(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50: 4.50E+4nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116039(3,5-Difluoro-4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl...)
Affinity DataIC50: 210nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed