BDBM50116027 3,5-Difluoro-4-(4-furan-2-yl-5-pyridin-4-yl-1H-imidazol-2-yl)-pyridine-2,6-diamine::CHEMBL66601

SMILES Nc1nc(N)c(F)c(-c2nc(-c3ccco3)c([nH]2)-c2ccncc2)c1F

InChI Key InChIKey=YQJXZKKQJNGAQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116027   

TargetProstaglandin G/H synthase 1(Sheep)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116027(3,5-Difluoro-4-(4-furan-2-yl-5-pyridin-4-yl-1H-imi...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50116027(3,5-Difluoro-4-(4-furan-2-yl-5-pyridin-4-yl-1H-imi...)
Affinity DataIC50: 670nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed