BDBM50115730 4-(Methyl-phenyl-amino)-[1,2]naphthoquinone::CHEMBL58292

SMILES CN(C1=CC(=O)C(=O)c2ccccc12)c1ccccc1

InChI Key InChIKey=GFOFRGPKZHUQDS-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50115730   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115730(4-(Methyl-phenyl-amino)-[1,2]naphthoquinone | CHEM...)
Affinity DataIC50: 3.49E+4nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50115730(4-(Methyl-phenyl-amino)-[1,2]naphthoquinone | CHEM...)
Affinity DataKi:  32nMAssay Description:Inhibition of human liver CES1 expressed in baculovirus infected sf9 cells using oseltamivir as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50115730(4-(Methyl-phenyl-amino)-[1,2]naphthoquinone | CHEM...)
Affinity DataKi:  90nMAssay Description:Inhibition of human liver CES1 expressed in baculovirus infected sf9 cells using oseltamivir as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details Article
PubMed