BDBM50115715 5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-carbonitrile::CHEMBL56118

SMILES N#Cc1c[nH]c(CN2CCN(CC2)c2ccccc2)c1

InChI Key InChIKey=IKBANCXZZJPIEB-UHFFFAOYSA-N

Data  7 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50115715   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115715(5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...)
Affinity DataEC50:  5.60nMAssay Description:Effective concentration of compound required against human Dopamine D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115715(5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...)
Affinity DataKi:  21nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D4 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115715(5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...)
Affinity DataKi:  450nMAssay Description:Ability to displace [3H]8-OH-DPAT radioligand from porcine 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115715(5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...)
Affinity DataKi:  610nMAssay Description:Ability to displace [3H]-Ketanserin radioligand from porcine 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115715(5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...)
Affinity DataKi:  1.80E+3nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D3 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115715(5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...)
Affinity DataKi:  3.70E+3nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115715(5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...)
Affinity DataKi:  4.60E+3nMAssay Description:Ability to displace [3H]SCH-23,390 radioligand from bovine Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50115715(5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-car...)
Affinity DataKi:  8.00E+3nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed