BDBM50115112 (Bis-phosphono-methyl)-(3-methyl-butyl)-ammonium::(isopentylamino)methylenediphosphonic acid::CHEMBL55856::[(3-Methyl-butylamino)-phosphono-methyl]-phosphonic acid::[[(3-methylbutyl)amino]methylene]-1,1-bisphosphonate

SMILES CC(C)CCN=C(P(O)(O)O)P(O)(O)=O

InChI Key InChIKey=CPMSBHPYDHPWQG-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115112   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50115112([[(3-methylbutyl)amino]methylene]-1,1-bisphosphona...)
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50115112([[(3-methylbutyl)amino]methylene]-1,1-bisphosphona...)
Affinity DataIC50: 830nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50115112([[(3-methylbutyl)amino]methylene]-1,1-bisphosphona...)
Affinity DataIC50: 490nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50115112([[(3-methylbutyl)amino]methylene]-1,1-bisphosphona...)
Affinity DataKi:  47nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed