BDBM50114998 4-(4-Chloro-phenyl)-3-(2-morpholin-4-yl-phenyl)-3H-thiazol-(2Z)-ylideneamine::CHEMBL50901

SMILES Clc1ccc(cc1)-c1csc(=N)n1-c1ccccc1N1CCOCC1

InChI Key InChIKey=NBAKCTOCDHUKRB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50114998   

TargetSodium-dependent serotonin transporter(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50114998(4-(4-Chloro-phenyl)-3-(2-morpholin-4-yl-phenyl)-3H...)
Affinity DataKi:  424nMAssay Description:Compound was tested for the inhibition of serotonin [3H]SER reuptake into rat forebrain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50114998(4-(4-Chloro-phenyl)-3-(2-morpholin-4-yl-phenyl)-3H...)
Affinity DataKi:  2.21E+4nMAssay Description:Compound was tested for the inhibition of norepinephrine [3H]NE reuptake into rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50114998(4-(4-Chloro-phenyl)-3-(2-morpholin-4-yl-phenyl)-3H...)
Affinity DataKi:  4.20E+4nMAssay Description:Tested for the ability to displace [3H]WIN-35 428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed