BDBM50114665 2-(trifluoromethyl)benzaldehyde thiosemicarbazone::CHEMBL91844

SMILES NC(=S)NN=Cc1cccc(Br)c1

InChI Key InChIKey=FGGWIXJNLRDBPW-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114665   

TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50114665(2-(trifluoromethyl)benzaldehyde thiosemicarbazone ...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrease(Jack bean)
Comsats Institute of Information Technology

Curated by ChEMBL
LigandPNGBDBM50114665(2-(trifluoromethyl)benzaldehyde thiosemicarbazone ...)
Affinity DataIC50: 767nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50114665(2-(trifluoromethyl)benzaldehyde thiosemicarbazone ...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzipain using Z-Phe-Arg-AMC as substrate preincubated for 5 mins followed by substrate addition by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetUrease(Jack bean)
Comsats Institute of Information Technology

Curated by ChEMBL
LigandPNGBDBM50114665(2-(trifluoromethyl)benzaldehyde thiosemicarbazone ...)
Affinity DataKi:  670nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed