BDBM50114649 (1E)-1-[3-(trifluoromethyl)phenyl]ethan-1-one thiosemicarbazone::CHEMBL330050

SMILES CC(=NNC(N)=S)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=TZKDKVOAUCBYJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114649   

TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50114649((1E)-1-[3-(trifluoromethyl)phenyl]ethan-1-one thio...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50114649((1E)-1-[3-(trifluoromethyl)phenyl]ethan-1-one thio...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzipain using Z-Phe-Arg-AMC as substrate preincubated for 5 mins followed by substrate addition by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed