BDBM50114642 5-(4-chlorophenyl)-2-furaldehyde semicarbazone::CHEMBL313316

SMILES NC(=O)NN=Cc1ccc(o1)-c1ccc(Cl)cc1

InChI Key InChIKey=ANUWWIQYOYPMTQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114642   

TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50114642(5-(4-chlorophenyl)-2-furaldehyde semicarbazone | C...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50114642(5-(4-chlorophenyl)-2-furaldehyde semicarbazone | C...)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50114642(5-(4-chlorophenyl)-2-furaldehyde semicarbazone | C...)
Affinity DataIC50: 570nMAssay Description:Inhibition of N-terminal FLAG-tagged human PRMT5 using histone H4 substrate incubated fro 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50114642(5-(4-chlorophenyl)-2-furaldehyde semicarbazone | C...)
Affinity DataIC50: 570nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed