BDBM50114606 1-methyl-1H-indole-2-carbaldehyde thiosemicarbazone::CHEMBL90808

SMILES Cn1c(C=NNC(N)=S)cc2ccccc12

InChI Key InChIKey=QHMNCTCVOBMQLU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114606   

TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50114606(1-methyl-1H-indole-2-carbaldehyde thiosemicarbazon...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Universite Grenoble

Curated by ChEMBL
LigandPNGBDBM50114606(1-methyl-1H-indole-2-carbaldehyde thiosemicarbazon...)
Affinity DataIC50: 1.70E+6nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate preincubated for 5 mins by spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed