BDBM50114586 2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-ethanol::CHEMBL297359

SMILES Nc1ncnc2n(CCO)cc(-c3ccc(Oc4ccccc4)cc3)c12

InChI Key InChIKey=AFGOFEFLRMONQO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50114586   

TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50114586(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human p56 Lck tyrosine kinase (lck64-509)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50114586(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50114586(2-[4-Amino-5-(4-phenoxy-phenyl)-pyrrolo[2,3-d]pyri...)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of TIE-2 kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed