BDBM50114479 2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carbamimidoyl-phenoxy)-phenyl]-amide::CHEMBL297835

SMILES NC(=N)c1cccc(Oc2ccccc2NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1

InChI Key InChIKey=DUVLBBOBLCROSD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50114479   

TargetKallikrein-1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114479(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 250nMAssay Description:Tested in vitro for the inhibitory activity against kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114479(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 1.81E+5nMAssay Description:Tested in vitro for the inhibitory activity against activated protein C (APC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114479(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 1.10E+4nMAssay Description:Tested in vitro for the inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114479(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 1.80E+4nMAssay Description:Tested in vitro for the inhibitory activity against Tissue plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114479(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 4.30E+4nMAssay Description:Tested in vitro for the inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114479(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 970nMAssay Description:Tested in vitro for the inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114479(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 3.60nMAssay Description:Tested in vitro for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50114479(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carb...)
Affinity DataIC50: 3.60nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed