BDBM50114298 2-[5-Chloro-4-(propane-1-sulfonyl)-pyridin-2-ylamino]-3-{4-[(3,5-dichloro-pyridine-4-carbonyl)-amino]-phenyl}-propionic acid::CHEMBL41089

SMILES CCCS(=O)(=O)c1cc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(O)=O)ncc1Cl

InChI Key InChIKey=LSIDNIOTAONRRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114298   

TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114298(2-[5-Chloro-4-(propane-1-sulfonyl)-pyridin-2-ylami...)
Affinity DataIC50: 4nMAssay Description:Inhibition of very late antigen 4 from HL60 lysate in a protein-based ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114298(2-[5-Chloro-4-(propane-1-sulfonyl)-pyridin-2-ylami...)
Affinity DataIC50: 70nMAssay Description:Inhibition of very late antigen 4 expressed in Jurkat cell line, in a cell-based adhesion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed