BDBM50114073 CHEMBL3604010::US20240327372, Compound Racemic methylone

SMILES CNC(C)C(=O)c1ccc2OCOc2c1

InChI Key InChIKey=VKEQBMCRQDSRET-UHFFFAOYSA-N

Data  3 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50114073   

TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataEC50:  133nMAssay Description:Binding affinity to DAT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]MPP+ release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataEC50:  242nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataIC50: 1.23E+4nMAssay Description:Competition binding assays were carried out in 96-well polypropylene plates in a final volume of 250 μL per well. To each well was added 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataIC50: 7.11E+3nMAssay Description:Competition binding assays were carried out in 96-well polypropylene plates in a final volume of 250 μL per well. To each well was added 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Rat)
Transcend Therapeutics

US Patent
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataIC50: 3.10E+3nMAssay Description:Competition binding assays were carried out in 96-well polypropylene plates in a final volume of 250 μL per well. To each well was added 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Rat)
Transcend Therapeutics

US Patent
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataKi:  1.46E+3nMAssay Description:Competition binding assays were carried out in 96-well polypropylene plates in a final volume of 250 μL per well. To each well was added 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataKi:  3.53E+3nMAssay Description:Competition binding assays were carried out in 96-well polypropylene plates in a final volume of 250 μL per well. To each well was added 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50114073(CHEMBL3604010 | US20240327372, Compound Racemic me...)
Affinity DataKi:  7.44E+3nMAssay Description:Competition binding assays were carried out in 96-well polypropylene plates in a final volume of 250 μL per well. To each well was added 150 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent