BDBM50114048 CHEMBL3605410

SMILES c1cc(c(cc1Br)N)C(=O)NC2(CCCCC2)C(=O)NCC#N

InChI Key InChIKey=KVQZUZVIKTWMTQ-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114048   

TargetCathepsin K(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114048(CHEMBL3605410)
Affinity DataKi:  10nMAssay Description:Inhibition of human cathepsin-K using Z-Gly-Pro-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProcathepsin L(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114048(CHEMBL3605410)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed