BDBM50113971 CHEMBL3605506

SMILES Nc1ccccc1NC(=O)c1ccc(CNC2=N[C@@H]([C@@H](O2)c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=FYAWEPJUGYZQDE-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50113971   

TargetHistone deacetylase 1(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 80nMAssay Description:Inhibition of C-flagged recombinant HDAC1 (unknown origin) pre-incubated for 1 hr before substrate addition by homogeneous fluorogenic HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 110nMAssay Description:Inhibition of His-tagged recombinant HDAC2 (1 to 488 residues) (unknown origin) pre-incubated for 3 hrs before substrate addition by homogeneous fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant HDAC3/NCOR2 (unknown origin) pre-incubated for 3 hrs before substrate addition by homogeneous fluorogenic HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 2.52E+4nMAssay Description:Inhibition of His-flagged recombinant HDAC8 (unknown origin) expressed in Escherichia coli BL21 pre-incubated for 15 mins before substrate addition b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113971(CHEMBL3605506)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed