BDBM50113970 CHEMBL3605504

SMILES Nc1ccccc1NC(=O)c1ccc(CNC2=NC(CO2)(c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=SRIRSXLHDKCIBH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113970   

TargetHistone deacetylase 2(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113970(CHEMBL3605504)
Affinity DataIC50: 400nMAssay Description:Inhibition of His-tagged recombinant HDAC2 (1 to 488 residues) (unknown origin) pre-incubated for 3 hrs before substrate addition by homogeneous fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113970(CHEMBL3605504)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant HDAC3/NCOR2 (unknown origin) pre-incubated for 3 hrs before substrate addition by homogeneous fluorogenic HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50113970(CHEMBL3605504)
Affinity DataIC50: 5.35E+4nMAssay Description:Inhibition of His-flagged recombinant HDAC8 (unknown origin) expressed in Escherichia coli BL21 pre-incubated for 15 mins before substrate addition b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed