BDBM50113917 3-[3,5-Difluoro-4-methyl-6-(3-trifluoromethyl-phenoxy)-pyridin-2-yloxy]-benzamidine::CHEMBL83003

SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(F)(F)F)c1F

InChI Key InChIKey=SUJUCOWQSJUBAX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113917   

TargetCoagulation factor X(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50113917(3-[3,5-Difluoro-4-methyl-6-(3-trifluoromethyl-phen...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human Coagulation factor X was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50113917(3-[3,5-Difluoro-4-methyl-6-(3-trifluoromethyl-phen...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory constant against human coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50113917(3-[3,5-Difluoro-4-methyl-6-(3-trifluoromethyl-phen...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory constant against human coagulation factor II (thrombin) for selectivity within coagulation cascadeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed