BDBM50113806 4-(3,3-Diphenyl-propyl)-5-piperidin-4-yl-isoxazol-3-ol; hydrobromide::CHEMBL377925::CHEMBL544544

SMILES O=c1[nH]oc(C2CCNCC2)c1CCC(c1ccccc1)c1ccccc1

InChI Key InChIKey=FJADGXRCKLHLAK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113806   

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50113806(CHEMBL544544 | CHEMBL377925 | 4-(3,3-Diphenyl-prop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50113806(CHEMBL544544 | CHEMBL377925 | 4-(3,3-Diphenyl-prop...)
Affinity DataKi:  20nMAssay Description:Binding affinity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by voltage-clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed