BDBM50113678 1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-acetyl}-pyrrolidine-2-carbonitrile::CHEMBL77539

SMILES [O-][N+](=O)c1ccc(NCCNCC(=O)N2CCC[C@H]2C#N)nc1

InChI Key InChIKey=VEHQFHWMDLMEIN-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50113678   

TargetDipeptidyl peptidase 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from rat plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 8.70nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibitory activity against Dipeptidylpeptidase II (DPP-II) extracted from bovine kidney homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 17.3nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from rat plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 8.73nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 1.60E+4nMAssay Description:In vitro inhibitory activity against Post-proline cleaving enzyme (PPCE) obtained from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50113678(1-{2-[2-(5-Nitro-pyridin-2-ylamino)-ethylamino]-ac...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase II (DPP II) obtained form bovine kidney homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed