BDBM50113591 (E)-3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoic acid (3-fluoro-2'-sulfamoyl-biphenyl-4-yl)-amide::3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoic acid (3-fluoro-2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL287252

SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N

InChI Key InChIKey=ZABMZZGTXQGHII-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50113591   

TargetProthrombin(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113591(3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against Factor IIa (serine protease) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113591(3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataIC50: 194nMAssay Description:Inhibitory activity against trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113591(3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50113591(3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoic ac...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory concentration to coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed