BDBM50113569 (R)-2-[(S)-1-Carboxy-2-(2'-methoxy-biphenyl-4-yl)-ethylcarbamoyl]-tetrahydro-furan-2-carboxylic acid ethyl ester::CHEMBL38145

SMILES CCOC(=O)[C@@]1(CCCO1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1OC)C(O)=O

InChI Key InChIKey=LHDSVLWAOHWRLU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113569   

TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113569((R)-2-[(S)-1-Carboxy-2-(2'-methoxy-biphenyl-4-yl)-...)
Affinity DataIC50: 51nMAssay Description:Inhibition of alpha4-beta7 antigen with MAdCAM immunoglobulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113569((R)-2-[(S)-1-Carboxy-2-(2'-methoxy-biphenyl-4-yl)-...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of alpha4-beta1 (very late) antigen binding with VCAM-1 immunoglobulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113569((R)-2-[(S)-1-Carboxy-2-(2'-methoxy-biphenyl-4-yl)-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of alpha4-beta1 (very late) antigen binding with VCAM-1 immunoglobulin plus 5% human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed