BDBM50113549 (S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[(S)-2-(4-trifluoromethyl-phenyl)-tetrahydro-furan-2-carbonyl]-amino}-propionic acid::CHEMBL285721

SMILES COc1ccccc1-c1ccc(C[C@H](NC(=O)[C@]2(CCCO2)c2ccc(cc2)C(F)(F)F)C(O)=O)cc1

InChI Key InChIKey=ZYJZNWWXHXUROK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113549   

TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113549((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[(S)-2-(4-trif...)
Affinity DataIC50: 120nMAssay Description:Inhibition of alpha4-beta1 (very late) antigen binding with VCAM-1 immunoglobulin plus 5% human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113549((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[(S)-2-(4-trif...)
Affinity DataIC50: 504nMAssay Description:Inhibition of alpha4-beta7 antigen with MAdCAM immunoglobulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50113549((S)-3-(2'-Methoxy-biphenyl-4-yl)-2-{[(S)-2-(4-trif...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of alpha4-beta1 (very late) antigen binding with VCAM-1 immunoglobulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed