BDBM50113423 4-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-pyridin-4-yl)-ethyl]-N-(2-methyl-benzoyl)-benzenesulfonamide::CHEMBL287114

SMILES Cc1ccccc1C(=O)NS(=O)(=O)c1ccc(cc1)C(Cc1cc[n+]([O-])cc1)c1ccc(OC(F)F)c(OC(F)F)c1

InChI Key InChIKey=ZRWBSLBYMVRMGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113423   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50113423(4-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-pyr...)
Affinity DataIC50: 3.10nMAssay Description:Inhibitory concentration against human PDE4A isoform using a construct representing the common region of spliced variants expressed as GST-fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50113423(4-[1-(3,4-Bis-difluoromethoxy-phenyl)-2-(1-oxy-pyr...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory concentration of compound against LPS- induced TNF-alpha production in whole human blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed