BDBM50113348 5-[1,2]Dithiolan-3-yl-pentanoic acid::CHEMBL33240::CHEMBL541555

SMILES NC(=Nc1ccccc1)c1cccs1

InChI Key InChIKey=RCORNHOUCUDCAC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113348   

TargetNitric oxide synthase, brain(Human)
Institute Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50113348(CHEMBL33240 | CHEMBL541555 | 5-[1,2]Dithiolan-3-yl...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition concentration was evaluated on the effect of conversion by Nitric oxide synthase of [3H]L-arginine into [3H]L-citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50113348(CHEMBL33240 | CHEMBL541555 | 5-[1,2]Dithiolan-3-yl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory concentration tested against neuronal nitric oxide synthase (nNOS ) from rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50113348(CHEMBL33240 | CHEMBL541555 | 5-[1,2]Dithiolan-3-yl...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed