BDBM50113317 Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naphthalene-1,3-disulfonic acid](Chicago Sky Blue)::CHEMBL311909

SMILES COc1c(ccc(c1)c2cc(c(cc2)/N=N/c3c(c4c(c(cc(c4cc3)S(=O)(=O)O)S(=O)(=O)O)N)O)OC)/N=N/c5c(c6c(c(cc(c6cc5)S(=O)(=O)O)S(=O)(=O)O)N)O

InChI Key InChIKey=OHMJKMNGYYWCHB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113317   

TargetSodium/bile acid cotransporter(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50113317(Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of preS1-peptide binding to human HA-tagged NTCP in U2OS expresseing NTCP in incubated for 24 hrs using Myrcludex B as substrate by compet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetSodium/bile acid cotransporter(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50113317(Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naph...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human NTCP mediated TCA uptake in U2OS expresseing HA-tagged NTCP cells preincubated for 10 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVesicular glutamate transporter 3(Rat)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50113317(Bis[4-Amino-5-hydroxy-6-(2-methoxy-phenylazo)-naph...)
Affinity DataKi:  190nMAssay Description:Evaluated for competitive inhibition against Vesicular glutamate transporter (VGLUT), and Ki value was reported.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed