BDBM50113043 (2R,4S)-1-[4-(3-Fluoro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28299

SMILES ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2cccc(F)c2)cc1

InChI Key InChIKey=GPJUMXDCOLWYIL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50113043   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113043((2R,4S)-1-[4-(3-Fluoro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against Matrix metalloprotease-1 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50113043((2R,4S)-1-[4-(3-Fluoro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration against recombinant tumor necrosis factor alpha converting enzyme More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50113043((2R,4S)-1-[4-(3-Fluoro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of TNF-alpha release was determined in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed