BDBM50112787 1-(2-Ethoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine; hydrochloride::CHEMBL557829

SMILES CCOc1ccccc1N1CCN(CCCCc2cc(no2)-c2cccs2)CC1

InChI Key InChIKey=YHQGUYGNJMOBOA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112787   

TargetD(3) dopamine receptor(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50112787(1-(2-Ethoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol...)
Affinity DataKi:  3.90nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50112787(1-(2-Ethoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol...)
Affinity DataKi:  12nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50112787(1-(2-Ethoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol...)
Affinity DataKi:  194nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human Dopamine receptor D2 long expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed