BDBM50112748 (R)-2-Benzo[1,3]dioxol-5-yl-4-butyl-6-isopropoxy-2H-chromene-3-carboxylic acid::2-Benzo[1,3]dioxol-5-yl-4-butyl-6-isopropoxy-2H-chromene-3-carboxylic acid::CHEMBL62264

SMILES CCCCC1=C([C@H](Oc2ccc(OC(C)C)cc12)c1ccc2OCOc2c1)C(O)=O

InChI Key InChIKey=GOMOLLUWOMVWFU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112748   

TargetEndothelin receptor type B(Pig)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112748(2-Benzo[1,3]dioxol-5-yl-4-butyl-6-isopropoxy-2H-ch...)
Affinity DataIC50: 400nMAssay Description:Binding affinity to endothelin B receptor measured by inhibition of [125I]ET-3 binding recombinant pig ET-B receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112748(2-Benzo[1,3]dioxol-5-yl-4-butyl-6-isopropoxy-2H-ch...)
Affinity DataIC50: 0.420nMAssay Description:Binding affinity for endothelin A receptor by inhibition of [125I]ET1 binding in rat aorta smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50112748(2-Benzo[1,3]dioxol-5-yl-4-butyl-6-isopropoxy-2H-ch...)
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50112748(2-Benzo[1,3]dioxol-5-yl-4-butyl-6-isopropoxy-2H-ch...)
Affinity DataIC50: 0.420nMAssay Description:Ability to displace [125I]ET1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed