BDBM50112576 2-(3-(3,4-dichlorobenzylamino)propylamino)quinolin-4(1H)-one::2-[3-(3,4-Dichloro-benzylamino)-propylamino]-1H-quinolin-4-one::CHEMBL60402

SMILES Oc1cc(NCCCNCc2ccc(Cl)c(Cl)c2)nc2ccccc12

InChI Key InChIKey=NSDYJDCKWMOUKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112576   

LigandPNGBDBM50112576(2-[3-(3,4-Dichloro-benzylamino)-propylamino]-1H-qu...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory concentration against Methionyl-tRNA synthetase in a pyrophosphate exchange assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine--tRNA ligase(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50112576(2-[3-(3,4-Dichloro-benzylamino)-propylamino]-1H-qu...)
Affinity DataIC50: 16nMAssay Description:Compound tested for inhibition of Staphylococcus aureus MRS (methionyl tRNA synthetase) in aminoacylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed