BDBM50112552 2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-(4-hydroxy-butyl)-acetamide::2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}-N-(4-hydroxybutyl)acetamide::CHEMBL24837

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NCCCCO)c2c1

InChI Key InChIKey=GFCKKPYXWBFRGZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50112552   

TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50112552(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibitory concentration against prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50112552(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50112552(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112552(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed