BDBM50112504 4-Hydroxy-3-{3-[4-(1-methanesulfonyl-piperidin-4-yloxy)-3-trifluoromethyl-phenylamino]-propenyl}-benzamidine::CHEMBL24287

SMILES CS(=O)(=O)N1CCC(CC1)Oc1ccc(NC\C=C\c2cc(ccc2O)C(N)=N)cc1C(F)(F)F

InChI Key InChIKey=CRUGEYOXRXIBLR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112504   

TargetCoagulation factor X(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112504(4-Hydroxy-3-{3-[4-(1-methanesulfonyl-piperidin-4-y...)
Affinity DataKi:  44nMAssay Description:Competitive inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112504(4-Hydroxy-3-{3-[4-(1-methanesulfonyl-piperidin-4-y...)
Affinity DataKi:  890nMAssay Description:Competitive inhibition of coagulation factor IIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112504(4-Hydroxy-3-{3-[4-(1-methanesulfonyl-piperidin-4-y...)
Affinity DataKi:  1.25E+3nMAssay Description:Competitive inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed