BDBM50112384 1-(3-Chloro-phenyl)-4-[3-(2'-methoxy-4'-trifluoromethyl-biphenyl-4-ylmethyl)-3H-imidazol-4-ylmethyl]-piperazin-2-one::CHEMBL22675

SMILES COc1cc(ccc1-c1ccc(Cn2cncc2CN2CCN(C(=O)C2)c2cccc(Cl)c2)cc1)C(F)(F)F

InChI Key InChIKey=NKZRKBVNTOVNAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112384   

LigandPNGBDBM50112384(1-(3-Chloro-phenyl)-4-[3-(2'-methoxy-4'-trifluorom...)
Affinity DataIC50: 392nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50112384(1-(3-Chloro-phenyl)-4-[3-(2'-methoxy-4'-trifluorom...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed