BDBM50112378 17-butyl-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22,5.114,18.08,12.023,27]hentriaconta-1(27),8,10,14(31),15,17,20(28),21,23,25-decaen-3-one::CHEMBL283793

SMILES CCCCc1ccc2Cn3cncc3CCN3CCN(C(=O)C3)c3cccc4ccc(Oc1c2)cc34

InChI Key InChIKey=VBTFFQXCBWFXEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112378   

LigandPNGBDBM50112378(17-butyl-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2...)
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50112378(17-butyl-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed