BDBM50112141 CHEMBL3609869::US9464044, 3

SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4ccccc4F)CC1)C(C3)C2

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112141   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112141(US9464044, 3 | CHEMBL3609869)
Affinity DataIC50: 6.20nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112141(US9464044, 3 | CHEMBL3609869)
Affinity DataIC50: 6nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112141(US9464044, 3 | CHEMBL3609869)
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed