BDBM501121 7-((6- ((dimethylamino)- methyl)-5- ((lS,3S)-3- methoxycyclo pentyl)pyridin- 2-yl)amino)-4- (7-fluoroimidazo [1,2-a]pyridin- 3-yl)isoindolm- 1-one::US11021481, Compound I-793::US11548890, Compound I-793

SMILES CO[C@@H]1CCC(C1)c1ccc(Nc2ccc(c3CNC(=O)c23)-c2cnc3cc(F)ccn23)nc1CN(C)C

InChI Key InChIKey=OVFNUKNGRDZILC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501121   

LigandPNGBDBM501121(US11021481, Compound I-793 | 7-((6- ((dimethylamin...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM501121(US11021481, Compound I-793 | 7-((6- ((dimethylamin...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent