BDBM50111802 1N-[2-hydroxy-5-oxo-(3S)-dihydro-3-furanyl]-2-[2-oxo-3-phenylcarboxamido-5-(3-phenylpropanoyl)-(3S)-2,5-dihydro-1H-benzo[b][1,4]diazepin-1-yl]acetamide::CHEMBL283789

SMILES OC1OC(=O)C[C@@H]1NC(=O)CN1c2ccccc2N(C[C@H](NC(=O)c2ccccc2)C1=O)C(=O)CCc1ccccc1

InChI Key InChIKey=GWZOQIZRODZXML-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111802   

TargetCaspase-1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50111802(1N-[2-hydroxy-5-oxo-(3S)-dihydro-3-furanyl]-2-[2-o...)
Affinity DataKi:  90nMAssay Description:Compound was tested for inhibitory activity against IL-1 beta converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50111802(1N-[2-hydroxy-5-oxo-(3S)-dihydro-3-furanyl]-2-[2-o...)
Affinity DataKi:  90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed