BDBM50111752 CHEMBL3605107

SMILES CNC(=O)Cn1cc(cn1)-c1cnc(N)c2c(csc12)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=VRWXMNHRCGQXDD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50111752   

TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111752(CHEMBL3605107)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111752(CHEMBL3605107)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111752(CHEMBL3605107)
Affinity DataIC50: 284nMAssay Description:Inhibition of KDR (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111752(CHEMBL3605107)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) using poly (Glu-Tyr, 4:1) substrate incubated for 60 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111752(CHEMBL3605107)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant BTK incubated for 5 mins by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111752(CHEMBL3605107)
Affinity DataIC50: 13nMAssay Description:Inhibition of BTK (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed