BDBM50111592 6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiophenylidene]-3,3'-dione::CHEMBL45343

SMILES Oc1c2c(cc(Cl)cc2=C)s\c1=c1\sc2cc(Cl)cc(=C)c2c1O

InChI Key InChIKey=ZATNBKBMTXYJPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50111592   

TargetBeta-galactosidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111592(6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiop...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of Beta-galactosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111592(6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiop...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111592(6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiop...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory activity against cloned Dihydrofolate reductase (cDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111592(6,6'-Dichloro-4,4'-dimethyl-[2,2']bi[benzo[b]thiop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed