BDBM50111212 2-(4,6-Dimethoxy-pyrimidin-2-yl)-4H-isoquinoline-1,3-dione::CHEMBL441214

SMILES COc1cc(OC)nc(n1)-n1c(O)cc2ccccc2c1=O

InChI Key InChIKey=XNZBJPREYBLRJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111212   

TargetProstaglandin G/H synthase 2(Sheep)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50111212(2-(4,6-Dimethoxy-pyrimidin-2-yl)-4H-isoquinoline-1...)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibitory activity (RA2) against Prostaglandin G/H synthase 2 was calculated relative to aspirinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50111212(2-(4,6-Dimethoxy-pyrimidin-2-yl)-4H-isoquinoline-1...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibitory activity (RA1) against Prostaglandin G/H synthase 1 was calculated relative to aspirinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed