BDBM50111210 2-(3,5-Dimethyl-phenyl)-4H-isoquinoline-1,3-dione::CHEMBL8783

SMILES Cc1cc(C)cc(c1)-n1c(O)cc2ccccc2c1=O

InChI Key InChIKey=NLCVVBLKNZQCIA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50111210   

TargetProstaglandin G/H synthase 1(Sheep)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50111210(2-(3,5-Dimethyl-phenyl)-4H-isoquinoline-1,3-dione ...)
Affinity DataIC50: 9.52E+4nMAssay Description:Inhibitory activity (RA1) against Prostaglandin G/H synthase 1 was calculated relative to aspirinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50111210(2-(3,5-Dimethyl-phenyl)-4H-isoquinoline-1,3-dione ...)
Affinity DataIC50: 3.85E+4nMAssay Description:Inhibitory activity (RA2) against Prostaglandin G/H synthase 2 was calculated relative to aspirinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50111210(2-(3,5-Dimethyl-phenyl)-4H-isoquinoline-1,3-dione ...)
Affinity DataIC50: 3.76E+5nMAssay Description:Inhibitory activity against dipeptidyl peptidase IV (DPP- IV)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50111210(2-(3,5-Dimethyl-phenyl)-4H-isoquinoline-1,3-dione ...)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed