BDBM501109 4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- (((R)-3- methoxypyrrol- idin-1- yl)methyl)-5- ((S)- tetrahydrofuran- 3-yl)pyridin- 2- yl)amino)isoin- dolin-1-one::US11021481, Compound I-781::US11078201, Compound I-781::US11548890, Compound I-781

SMILES CO[C@@H]1CCN(Cc2nc(Nc3ccc(c4CNC(=O)c34)-c3cnc4cc(F)ccn34)ccc2[C@@H]2CCOC2)C1

InChI Key InChIKey=JLDVJNXHSYSYLO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 501109   

LigandPNGBDBM501109(US11021481, Compound I-781 | 4-(7- fluoroimidazo [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM501109(US11021481, Compound I-781 | 4-(7- fluoroimidazo [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM501109(US11021481, Compound I-781 | 4-(7- fluoroimidazo [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM501109(US11021481, Compound I-781 | 4-(7- fluoroimidazo [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM501109(US11021481, Compound I-781 | 4-(7- fluoroimidazo [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent