BDBM50110515 3-Fluoro-5-(2-isopropyl-4,4-dimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-benzonitrile::CHEMBL163833

SMILES CC(C)C1Nc2ccc(cc2C(C)(C)O1)-c1cc(F)cc(c1)C#N

InChI Key InChIKey=JSNIBELMASXADL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110515   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110515(3-Fluoro-5-(2-isopropyl-4,4-dimethyl-1,4-dihydro-2...)
Affinity DataIC50: 47nMAssay Description:Antagonistic activity against Progesterone receptor (PR) in transcriptional activation assay in human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110515(3-Fluoro-5-(2-isopropyl-4,4-dimethyl-1,4-dihydro-2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed