BDBM50110513 6-(3-Cyano-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine-2-carboxylic acid ethyl ester::CHEMBL165055

SMILES CCOC(=O)C1Nc2ccc(cc2C(C)(C)O1)-c1cc(F)cc(c1)C#N

InChI Key InChIKey=SWLNWRPERFZMQP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110513   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110513(6-(3-Cyano-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihyd...)
Affinity DataIC50: 1.79E+3nMAssay Description:Binding affinity against progesterone receptor using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110513(6-(3-Cyano-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihyd...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110513(6-(3-Cyano-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihyd...)
Affinity DataIC50: 159nMAssay Description:Binding affinity against progesterone receptor using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed