BDBM50110512 2,2-Dimethyl-propionic acid 6-(5-cyano-thiophen-3-yl)-4,4-dimethyl-2-trifluoromethyl-4H-benzo[d][1,3]oxazin-1-ylmethyl ester::CHEMBL351751

SMILES CC(C)(C)C(=O)OCN1C(OC(C)(C)c2cc(ccc12)-c1csc(c1)C#N)C(F)(F)F

InChI Key InChIKey=TZSPNXHHNKONFA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110512   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110512(2,2-Dimethyl-propionic acid 6-(5-cyano-thiophen-3-...)
Affinity DataEC50:  0.900nMAssay Description:Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110512(2,2-Dimethyl-propionic acid 6-(5-cyano-thiophen-3-...)
Affinity DataIC50: 7.90nMAssay Description:Binding affinity against progesterone receptor using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed